Wednesday 1 February 2012

U.K. agency tentatively OKs proposed research with hybrid human-animal embryos

LONDON - British authorities on Thursday approved scientists' use of animal eggs to create human stem cells, a ruling that is expected to boost the supply of stem cells for research.

The decision means that researchers will be able to refine their techniques for producing human stem cells by practising first on animal eggs, of which there is a steady supply. Similar work involving human-animal stem cells is also underway in China and the United States.

"This is good news for research, but most importantly, it is good news for patients," said Sophie Petit-Zeman of the Association of Medical Research Charities.

Scientists have been exploring the use of stem cells to cure many degenerative diseases such as Parkinson's, since the cells have the ability to develop into any cell in the human body.

The Human Fertilization and Embryology Authority said it had granted conditional one-year licences to two institutions to conduct research using mixed human-animal embryos. In Britain, all research involving human eggs and embryos must be approved by the authority.

Scientists from King's College and Newcastle University submitted applications last year to create human stem cells using animal eggs.

The process involves injecting an empty cow or rabbit egg with human DNA. A burst of electricity is then used to trick the egg into dividing regularly, so that it becomes a very early embryo, from which stem cells can be extracted.

"Cow eggs seem to be every bit as good at doing this job as human eggs," said Lyle Armstrong of Newcastle University.

Because the animal cell's nucleus would be removed before human DNA was added, scientists said the resulting egg would not be a chimera. The embryos would not be allowed to develop for more than two weeks.

"We will only use them as a scientific tool and we need not worry about cells being derived from them everbeing used to treat human diseases," Armstrong said.



NEWS BY:http://www.ngnews.ca/Health/2008-01-18/article-310334/UK-agency-tentatively-OKs-proposed-research-with-hybrid-humananimal-embryos/1

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